Returning to France without any warrior fame but closely attached by this time to the Guises, Brantôme took to a Court life. He assisted in a tournament between the grand-prior, François de Guise, disguised as an Egyptian woman, "having on her arm a little monkey swaddled as an infant, which kept its baby face there is no telling how," and M. de Nemours, dressed as a bourgeoise housekeeper wearing at her belt more than a hundred keys attached to a thick silver chain. He witnessed the terrible scene of the execution of the Huguenot nobles at Amboise (March, 1560); was at Orléans when the Prince de Condé was arrested, and at Poissy for the reception of the Knights of Saint-Michel. In short, he was no more "home-keeping" in France than in foreign parts.
Charles IX., then about ten years old, succeeded his brother François II. in December, 1560. The following year Duc François de Guise was commissioned to escort his niece, Marie Stuart, to Scotland. Brantôme went with them, saw the threatening reception given to the queen by her sullen subjects, and then returned with the duke by way of England. In London, Queen Elizabeth greeted them most graciously, deigning to dance more than once with Duc François, to whom she said: "Monsieur mon prieur" (that was how she called him) "I like you very much, but not your brother, who tore my town of Calais from me."
Brantôme returned to France at the moment when the edict of Saint-Germain granting to Protestants the exercise of their religion was promulgated, and he was struck by the change of aspect presented by the Court and the whole nation. The two armed parties were face to face; the Calvinists, scarcely escaped from persecution, seemed certain of approaching triumph; the Prince de Condé, with four hundred gentlemen, escorted the preachers to Charenton through the midst of a quivering population. "Death to papists!"--the very cry Brantôme had first heard on landing in Scotland, where it sounded so ill to his ears--was beginning to be heard in France, to which the cry of "Death to the Huguenots!" responded in the breasts of an irritated populace. Brantôme did not hesitate as to the side he should take,--he was abbé, and attached to the Guises; he fought through the war with them, took part in the sieges of Blois, Bourges, and Rouen, was present at the battle of Dreux, where he lost his protector the grand-prior, and attached himself henceforth to François de Guise, the elder, whom he followed to the siege of Orléans in 1563, where the duke was assassinated by Poltrot de Méré under circumstances which Brantôme has vividly described in his chapter on that great captain.