There have been several families who have been involved in South Indian cinema in a variety of professions related to the industry. For actors who featured in predominantly Hindi films rather than South Indian films, see List of Hindi film clans. Below is an incomplete list of families that have been involved in South Indian cinema.
A
Adivi family
Adivi Baapiraju, Indian polymath, novelist, fiction writer, and screen writer; cousin to Adivi Gangaraju Adivi Gangaraju, Nationalist, and Freedom fighter; Grandfather to Adivi Sesh Adivi Sesh, Actor, Screenwriter, Director; Grandson of Adivi Gangaraju Sai Kiran Adivi, Director; cousin to Adivi Sesh
Agathian family
Agathian, director. Kani Thiru, television personality; daughter of Agathian. Thiru, director; husband of Kani Vijayalakshmi Feroz, actress and television personality; daughter of Agathian. Feroz Mohammed, director; husband of Vijayalakshmi. Niranjani Ahathian, actress and costume designer; daughter of Agathian. Desingh Periyasamy, director; husband of Niranjani.
Ajith Kumar family
Ajith Kumar, actor. Shiva, actor; husband of Ajith's cousin, Priya. Shalini, former actress; wife of Ajith Kumar. Shamili, actress; sister of Shalini. Richard Rishi, actor; brother of Shalini.
Akkineni family
Akkineni Nageswara Rao, actor (d. 2014). Nagarjuna, actor. Daggubati Lakshmi, ex-wife of Nagarjuna Amala, actress; wife of Nagarjuna. Naga Chaitanya, actor; son of Nagarjuna and Daggubati Lakshmi. (see Daggubati family) Samantha, actress; ex- wife of Naga Chaitanya. Akhil, actor; son of Nagarjuna and Amala. Sumanth, actor; nephew of Nagarjuna. Sushanth, actor; nephew of Nagarjuna.
Ambareesh family
Chowdiah, musician
Ambareesh, actor-politician, grand-nephew Chowdiah
Sumalatha, actress-Politician, wife of Ambareesh
Abhishek Ambareesh, actor, son of Ambareesh and Sumalatha
Anant Nag family
Anant Nag, actor and producer
Gayathri, actress and wife of Ananth Nag
Shankar Nag, actor, director and producer, younger brother of Anant Nag
Arundhati Nag, actress, theater artist and wife of Shankar Nag
Padmavati Rao, sister of Arundhati Nag
Anandan family
C. L. Anandan, actor (d. 1989). Disco Shanthi, actress; daughter of C. L. Anandan. Srihari, actor; husband of Disco Shanthi. (d. 2013) Lalitha Kumari, actress, daughter of C. L. Anandan. Prakash Raj, actor; ex-husband of Lalitha Kumari. Pony Verma, choreographer; wife of Prakash Raj. Prasad Raj, actor; brother of Prakash Raj.
Asif Ali family
Asif Ali, actor
Askar Ali, actor, younger brother of Asif
Azhagappan family
A. L. Azhagappan, producer. A. L. Vijay, director; son of Azhagappan. Amala Paul, actress; ex-wife of Vijay. Udhaya, film actor; son of Azhagappan. Keerthika Udhaya, dubbing artiste; wife of Udhaya. Hamaresh, actor; grandson of Azhagappan.
B
Balasubrahmanyam family
S. P. Balasubrahmanyam, playback singer (d. 2020) S. P. B. Pallavi, playback singer; daughter of S. P. Balasubrahmanyam. S. P. B. Charan, playback singer; son of S. P. Balasubrahmanyam. S. P. Sailaja, playback singer; sister of S. P. Balasubrahmanyam. Subhalekha Sudhakar, actor; husband of S. P. Sailaja. K. Viswanath, actor and director; uncle of S. P. Balasubrahmanyam. Chandra Mohan, actor; cousin of K. Viswanath.
Bhagyaraj family
K. Bhagyaraj, director. Praveena Bhagyaraj (d. 1983), actress; late wife of Bhagyaraj Poornima Bhagyaraj, actress; wife of Bhagyaraj Saranya Bhagyaraj, actress; daughter of Bhagyaraj Shanthnu Bhagyaraj, actor; son of Bhagyaraj Keerthi Vijay, television personality; wife of Shanthnu. (see Subramanyam family)
Bhanupriya family
Bhanupriya, actress. Vindhya, actress; sister-in-law of Bhanupriya. Shantipriya, actress; sister of Bhanupriya. Siddharth Ray (d. 2004), actor; husband of Shantipriya. V. Shantaram (d. 1990), director; grandfather of Siddhanth Ray.
Bharathiraja family
Bharathiraja, actor and director. Jayaraj, actor; brother of Bharathiraja Manoj Bharathiraja, director; son of Bharathiraja. Nandana, actress; wife of Manoj. Manoj Kumar, director; brother-in-law of Director Bharathiraja.