Cuba is scheduled to compete at the 2023 Pan American Games in Santiago, Chile from October 20 to November 5, 2023. This was Cuba's 19th appearance at the Pan American Games, having competed at every edition of the games since the inaugural edition in 1951.
Boxer Julio César La Cruz and judoka Idalys Ortiz were the country's flagbearers during the opening ceremony.
Competitors
The following is the list of number of competitors (per gender) participating at the games per sport/discipline.
Medalists
The following Venezuelan competitors won medals at the games. In the by discipline sections below, medalists' names are bolded.
| style="text-align:left; width:78%; vertical-align:top;"|
Archery
Cuba qualified six archers (three men and three women) during the 2023 Copa Merengue.
Men
Women
Mixed
Artistic swimming
Cuba qualified a full team of nine artistic swimmers after the 2022 Central American and Caribbean Games.
Badminton
Cuba qualified a team of four athletes (two men and two women).
Men
Women
Mixed
Baseball
Summary
Cuba qualified a men's team (of 24 athletes) by finishing second in the 2023 Central American and Caribbean Games.
Group B
Basque pelota
Cuba qualified a team of six athletes (two men and four women) through the 2023 Pan American Basque Pelota Tournament.
Men
Women
Boxing
Cuba qualified 10 boxers (seven men and three women).
Men
Women
Canoeing
Sprint
Cuba qualified a total of 13 sprint athletes (seven men and six women).
Men
Women
Cycling
Cuba qualified a total of 2 cyclists (2 women).
Road
Cuba qualified 1 cyclist at the Caribbean Championships. Cuba also qualified 1 cyclist at the Pan American Championships.
Diving
Women
Fencing
Cuba qualified a team of 4 fencers (three men and one woman), through the 2022 Pan American Fencing Championships in Ascuncion, Paraguay.
Individual
Team
Field hockey
Summary
Women's tournament
Cuba qualified a women's team of 16 athletes by reaching the final of the 2023 Central American and Caribbean Games.
Group B
Gymnastics
Artistic
Cuba qualified a team of five male gymnasts in artistic at the 2023 Pan American Championships.
Men
Team & Individual Qualification
Qualification Legend: Q = Qualified to apparatus final
Rhythmic
Cuba qualified one individual gymnast.
Individual
Handball
Summary
Men's tournament
Cuba qualified a men's team (of 14 athletes) by reaching the final of the 2023 Central American and Caribbean Games.
Group B
Women's tournament
Cuba qualified a women's team (of 14 athletes) by reaching the final of the 2023 Central American and Caribbean Games.
Group B
Judo
Cuba has qualified 16 judokas (eight men and eight women).
Men
Women
Mixed
Karate
Cuba qualified three athletes (one man and two women) in the 2023 Central American and Caribbean Championship and the 2023 Pan American Championships.
Kumite
Modern pentathlon
Cuba qualified five modern pentathletes (three men and two women).
Racquetball
Cuba qualified a team of four racquetball players (two men and two women).
Roller sports
Speed
Men
Women
Rowing
Cuba qualified a team of 14 athletes (ten men and four women).
Men
Women
Sailing
Cuba qualified 3 boats for a total of 4 sailors.
Women
Mixed
Shooting
Cuba qualified a total of 14 shooters in the 2022 Americas Shooting Championships.
Men
Pistol and rifle
Men
Shotgun
Women
Pistol and rifle
Softball
Cuba qualified a women's team (of 18 athletes) by virtue of its campaign in the 2022 Pan American Championships.
Summary
Table tennis
Cuba qualified a full team of six athletes (three men and three women) through the 2023 Caribbean Championships.
Men
Women
Mixed
Taekwondo
Cuba qualified 8 athletes (four men and four women) during the Pan American Games Qualification Tournament.
Kyorugi
Poomsae (forms)
Triathlon
Cuba qualified a triathlon team of four athletes (two men and two women).