Jim Griffin, Jimmy Griffin or James Griffin may refer to:
Arts and entertainment
Jimmy Griffin (James Arthur Griffin, 1943–2005), American musician, member of Bread James J. Griffin (born 1949), American writer of Western novels James Griffin (songwriter), Australian singer / songwriter
Law and politics
James Griffin (Irish politician) (1899–1959), Irish Fianna Fáil politician
James D. Griffin (1929–2008), American politician; mayor of Buffalo, New York
James W. Griffin (born 1935), American politician in Iowa
James Griffin (Australian politician), member of the New South Wales Legislative Assembly
Sports
James Griffin (American football coach) (1918–1992), American football coach
James Griffin (defensive back) (born 1961), American football player
Jim Griffin (footballer) (born 1967), Scottish footballer for Motherwell FC
Others
James Aloysius Griffin (1883–1948), American prelate of the Roman Catholic Church James Bennett Griffin (1905–1997), American archaeologist James Griffin (philosopher) (1933–2019), American philosopher at University of Oxford James Anthony Griffin (born 1934), American prelate of the Roman Catholic Church James D. Griffin (scientist), American physician-scientist and cancer expert
Other uses
James Griffin Stadium, a stadium named after James S. Griffin, the first black police captain in St. Paul, MN