In the meantime poor Isis, in happy ignorance of all these things, was enjoying herself at the home of Henry Halse, one of the first discoverers of animal magnetism or mesmerism, and she proved a most agreeable subject for his experiments, was frequently put into a mesmeric state, and was very useful in diagnosing cases for Mr. Halse, who was utilising the new science in the cause of health. One morning he had placed her under the influence as usual, but she was so troubled and disturbed, and seemed to be suffering so much mental anxiety that Mr. Halse hastened to release her from the condition. On awakening, her sole thought was of London. "I must go to London at once," she cried, "I am needed in London, there is trouble there, I must go at once." Her friends tried to calm her, and said they would send to London and find out anything that might be taking place there; all to no purpose, they could not stay her for a moment. Her preparations were made in a very short time, and the first conveyance taken that could be had. Arrived in London, she went straight to No. 1, Bouverie Street, to learn if there was anything wrong at Enfield, only to find the whole household there, Enfield a thing of the past, and her beloved husband lying on what was to prove his death bed. She was in time only to be recognised and to assist in nursing him. The shock must have been terrible to her, from happiness to misery in a day. A few days of hope, of fearing, of watching with ceaseless anxiety, and all was over. As it neared the end Carlile roused himself from apparent unconsciousness, and with almost a superhuman effort said, with the greatest difficulty to those around him, "I am the same man I have always been, I have gone neither to the right nor to the left. My aim has been to accomplish one great purpose." This expression was uttered by a powerful effort of nature, and was the last that ever issued from his lips.
After the death of Carlile, and as soon as Isis had recovered somewhat from the shock, she went to visit awhile with the Ebworth ladies, taking her two daughters with her, a home being found for the little boy Julian at Harmony Hall, Robert Owen's school. Carlile having died intestate, his eldest son, Richard, succeeded to the business and stock of books, etc., as also a few months afterwards to the annuity, while Isis had only the furniture and personal property. She was thus left totally unprovided for. The sum of £200 a year which had been promised to her by the hitherto generous friends, and upon which Carlile relied, was not forthcoming, and Isis was left perfectly helpless, with three children under ten years of age to be fed, clothed and educated. In a few weeks she was given charge of the sewing room of the "Concordium", as Alcott House was named, where she for some months supported herself and her little daughters, Hypatia and Theophila; but the health of the former giving way she was removed to Charing Cross Hospital. Isis did not remain very many months at Alcott House, but having a small legacy left her by an aunt she removed to London, and taking a large house she furnished apartments. In this way and with the help of some generous friends she managed to keep her little family together. She devoted herself to their care and education, and being an expert needlewoman she always kept them and herself well and comfortably dressed. Being still young and very attractive she had many admirers and would-be lovers, and, as might be expected, many offers of marriage. Such offers had no attraction for her, but rather troubled her than anything else. Her children had some amusing stories to tell of baffled lovers and rejected proposals. Her beauty became rather an annoyance than a pleasure to her, because of the notice and attention it caused her. She seldom went out, and when she did she was always thickly veiled; yet her form and carriage drew the same attention.