Yotsuba&! is a manga written and drawn by Kiyohiko Azuma, and published in Japan by ASCII Media Works in the monthly magazine Dengeki Daioh. The chapters have been collected in 15 tankōbon volumes, with further chapters appearing in Dengeki Daioh to be collected in tankōbon format over time. The series was licensed in English by ADV Manga, with five volumes published; volume six was scheduled to be published February 2008 but was delayed indefinitely. Yen Press announced at New York Comic Con 2009 that they had acquired the North American license for the English release of the manga; volume six was released in September 2009 along with new translations of the first five volumes, with later volumes to follow. The series has been licensed in France by Kurokawa, in Spain by Norma Editorial, in Germany by Tokyopop Germany, in Italy by Dynit, in Finland by Punainen jättiläinen, in Korea by Daiwon C.I., in Taiwan by Kadokawa Media, in Vietnam by TVM Comics, and in Thailand by NED Comics.
Yotsuba&! follows the daily life of a young girl named Yotsuba Koiwai and her adoptive father, with each chapter taking place on a specific, nearly sequential day of a common year starting on Wednesday. The year was initially believed to be 2003, coinciding with the date of the manga's serialization, but Azuma has stated that the manga always takes place in the present day.
Official story dates through volume five are given by a small artbook, Yotsuba&! Illustrations and Materials, distributed in Japan with volume six and Yotsuba & Monochrome Animals; dates from volume six on are established by evidence within the series, such as statements by characters, and by statements by Azuma. The collected volumes have seven chapters each, spanning about a week in series time. The first five volumes cover a summer vacation period.
List of volumes and chapters
Note: This list uses official English-translated titles through volume 15, unofficial Japanese translations thereafter.
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| colspan="2" |Story date: 19 July 20 July (morning) 20 July (afternoon) 21 July 22 July 24 July 25 July |- style="border-bottom: 3px solid #093;" | colspan="5" | On the last day of the spring semester, Yotsuba and her father Koiwai move into their new house and meet the neighboring Ayase girls, Asagi, Fuuka, and Ena. As the Koiwais settle in, they encounter problems, including a broken bathroom lock and Yotsuba needing to learn about polite greetings, air conditioners, and the proper uses of doorbells. Fuuka offers the Koiwais her family's old television, and when Koiwai's friend Jumbo helps carry it, the Ayases are impressed by his height. For other household goods, Koiwai takes Yotsuba shopping at a department store for the first time. Jumbo takes Yotsuba and Ena cicada-catching, and they return to show off their catch to Mrs. Ayase. The next day, after Fuuka helps Yotsuba bring in the Koiwais' forgotten laundry, Yotsuba plays in the rain. |-
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| colspan="2" |Story date: 27 July 30 July 31 July 4 August 7 August 8 August 9 August |- style="border-bottom: 3px solid #093;" | colspan="5" | Yotsuba tags along when Ena and her friend Miura go drawing in the park. After watching a gangster movie, Yotsuba takes revenge on the Ayases with her water pistol. The next day, Mrs. Ayase sends Ena, Miura, and Yotsuba to buy cake from a bakery. After working all night on a deadline, Koiwai falls asleep, leaving Yotsuba to watch the house on her own. In a failed attempt to get closer to Asagi, Jumbo takes Yotsuba, Fuuka, and Ena swimming at the pool. When Yotsuba catches a bullfrog, Ena adores it but Miura is frightened of it. Asagi returns from an Okinawa vacation with souvenirs for her family—and leftover sata andagi for Yotsuba. |-
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| colspan="2" |Story date: 10 August (daytime) 10 August (evening) 11 August 12 August 14 August 16 August 17 August |- style="border-bottom: 3px solid #093;" | colspan="5" | To thank Asagi, Yotsuba travels to the playground for a souvenir for her and her friend Torako. In return, Asagi buys Yotsuba a package of fireworks. While helping Fuuka shop at Jumbo's flower shop, Yotsuba buys all the leftover stock for ¥10. The next day, during Obon, Koiwai sends Yotsuba, dressed as the "Flower Cupid," to give away excess flowers. The next day, Koiwai takes Yotsuba on her first visit to a zoo to see an elephant. In another attempt to get close to Asagi, Jumbo takes Yotsuba, Ena, and Miura to a fireworks show, where Yotsuba learns that crowds can be scary and that display fireworks are more impressive than firecrackers. |-