Harry Lee Colon (born February 14, 1969) is a former American football defensive back in the National Football League (NFL). After playing college football at Missouri, Colon was drafted by the New England Patriots in the eighth round (196th overall) of the 1991 NFL Draft. He played in the NFL for six years, playing for the New England Patriots (1991), the Detroit Lions (1992–1994, 1997), and the Jacksonville Jaguars (1995). He was selected by the Jacksonville Jaguars in the 1995 NFL expansion draft. He had to retire during the 1997 season due to a condition in his neck.
He now resides in Houston, Texas, where he is head coach of the football team and head of the athletics department at John H. Reagan High School.