The following list includes notable people who were born in or have lived in La Crosse, Wisconsin.
Academics
Donald J. Berthrong, historian
Ruth Boynton, physician and educator
Robert M. Dammon, professor and academic administrator
David Garbers, scientist
Adolph Gundersen, physician
Edward R. Hauser, animal scientist
William Duncan MacMillan, mathematician and astronomer
Curt Michel, NASA astronaut, professor
Louis Hermann Pammel, botanist
Walter Ristow, librarian
John O. Schwenn, psychologist and academic administrator
William A. Thompson, engineer
Blanche Wilkins Williams, educator of deaf students
Activists and journalists
Brynild Anundsen, Norwegian-American journalist
Harriet Bossnot, social and civic worker
Chris Bury, Nightline correspondent
James Cameron, civil rights activist
Tom Hanneman, sports broadcaster
Mark Kellogg, reporter (killed at the Battle of the Little Bighorn) Frieda S. Miller, labor and women's rights activist William Mullen, journalist Charles M. Palmer, organizer of the Associated Press Marcus M. Pomeroy, editor of the La Crosse Democrat newspaper during the Civil War George Edwin Taylor, activist and journalist Dave Umhoefer, Pulitzer Prize-winning journalist