The Professional Building is a historic office building located at Raleigh, North Carolina. It was designed by Yancey Milburn of the architectural firm Milburn, Heister & Company and built in 1925. It is an eight-story, steel frame and yellow brick veneer Classical Revival style skyscraper with Beaux Arts style terra cotta ornamental elements. It consists of a two-story "base", five-story "shaft" and one-story "capital" in the Chicago style.
It was listed on the National Register of Historic Places in 1983.