That time was marked, as was every crisis in the blood-stained career of Fredegond, by a murder. The weak and effeminate King himself fell a victim, and was slain (in 584) by unknown assassins as he was out hunting. In the confusion and lawlessness that ensued, Pretextatus returned from exile to Rouen, and Fredegond, who had placed herself under the protection of Gunthram, was sent to Rueil, a town in the domain of Rouen, near the meeting of the Eûre and Seine. Leaving for awhile in peace the old ecclesiastic who had had the insolence to come back to the dignities from which she had driven him, Fredegond turned at once to plot the destruction of her lifelong enemy, Brunhilda, who was now in a position of far greater security and honour than herself. But her emissary was obliged to return unsuccessful, and had his feet and hands cut off for his pains. A second attempt upon both mother and son failed equally, and then Fredegond, balked of her higher prey, took the victim that was nearest, and went out from Rueil to Rouen. It was not long before the quarrel that she sought was occasioned by the bishop, who seems to have added to his usual unwisdom a courage born of the hardships of seven years of exile. Answering a taunt flung at him by the deposed queen, he bitterly drew the contrast between their present positions, and their former relation to each other, and bade Fredegond look to the salvation of her soul and the education of her son, and leave the wickedness that had stained so many years of her life with blood.
She left him on the instant and without a word, "felle fervens," says Gregory; and indeed it was not long before her vengeance broke out in the usual way. As the bishop knelt in prayer soon afterwards before the altar of the Cathedral, her assassin drove his knife beneath his armpit, and Pretextatus was carried bleeding mortally to his chamber. Thither came the queen to gloat over her latest victim, begging him to say whose hand it was had done the deed, that so due punishment might be at once exacted. But he knew well who was the real murderess. "Quis haec fecit," replied the dying prelate, "nisi qui reges interemit, qui sepius sanguinem innocentium effudit, qui diversa in hoc regno mala commisit?"