Sante is both a masculine Italian given name and a surname. Notable people with the name include:
Given name: Sante Bentivoglio (1426–1462), Italian nobleman Sante Geronimo Caserio (1873–1894), Italian anarchist and assassin Sante Cattaneo (1739–1819), Italian Neoclassic painter Sante Ceccherini (1863–1932), Italian fencer Sante Gaiardoni (born 1939), Italian cyclist Sante Geminiani (1919–1951), Italian motorcycle racer Sante Graziani (1920–2005), American artist Sante Kimes (1934–2014), American murderer Sante Lombardo (1504–1560), Italian architect Sante Marsili (born 1950), Italian water polo player Sante Monachesi (born 1910), Italian painter Sante Poromaa (born 1958), Swedish Zen Buddhist priest Sante De Sanctis (1862–1935), Italian psychologist Sante Vandi (1653–1716), Italian Baroque painter
Surname: Lucy Sante (born 1954), Belgian-American writer and critic