Manuel Perez may refer to:
Arts and entertainment
Manuel Perez (musician) (1871–1946), American cornetist and bandleader
Manuel Perez (animator) (1914–1981), animator for Warner Bros. Cartoons
Manuel Pérez (director) (born 1939), Cuban film director
Manuel "Manny" Pérez Batista or Manny Pérez (born 1969), Dominican actor
Politics
V. Manuel Perez (born 1973), California State Assemblyman, 80th District
Manuel Pérez (President of Nicaragua) (died 1852), President of Nicaragua 1843–1844 Manuel Pérez (1735-1819), Lieutenant Governor of Upper Louisiana 1787-1792
Sports
Manuel Pérez Flores (born 1980), Mexican football player with CF Monterrey
Manuel Perez (footballer) (born 1991), French professional footballer
Manuel Pérez (boxer) (born 1984), Mexican-American professional boxer in the Lightweight division Manuel Pérez Brunicardi (born 1978), Spanish ski mountaineer Manny Perez (soccer) (born 1999), American soccer player Manuel Perez Benitez better known as El Cordobés, Spanish matador of the 1960s Manuel Pérez Luna (born 1966), Spanish wheelchair basketball player
Other
Manuel Pérez García (born 1979), Spanish academic
Manuel Pérez Jr. (1923–1945), American soldier and Medal of Honor recipient
Manuel Pérez (teacher) (1890–1951), Puerto Rican teacher and public servant
Manuel Pérez (guerrilla leader) (died 1988), leader of the Colombian National Liberation Army from the 1970s to 1998