In this paper, aimed at exploring the fundamental properties of isoperimetric region in $3$-manifold $(M^3,g)$ which is asymptotic to Anti-de Sitter-Schwarzschild manifold with scalar curvature $R\geq -6$, we prove that connected isoperimetric region $\{ D_i\}$ with $\mathcal{ H}_g ^3(D_i)\geq \delta_0>0$ cannot slide off to the infinity of $(M^3,g)$ provided that $(M^3,g)$ is not isometric to the hyperbolic space. Furthermore, we prove that isoperimetric region $\{ D_i\}$ with topological sphere $\{ \partial D_i\}$ as boundary is exhausting regions of $M$ if Hawking mass $m_H(\partial D_i)$ has uniform bound. In the case of exhausting isoperimetric region, we obtain a formula on expansion of isoperimetric profile in terms of renormalized volume.
Categories: math.DG