As soon as the instructions were delivered to the Jeronymites, Las Casas received the following order from the Cardinal-regent:
"The Queen and the King. Bartholomew de Las Casas, priest, native of the city of Seville, and resident of the island of Cuba which is in the Indies."
"For as much as we are informed that you have been and are resident in those parts for a long time, from which you know and are experienced in their affairs, especially in what touches the well-being and usefulness of the Indians, and you know and are acquainted with their life and conversation from having dwelt with them, and because we know your good zeal in our Lord's service, from which we hope that you will execute with all diligence and care what we shall charge and command you and will see to what contributes to the welfare of the souls and bodies of the Spaniards and Indians who live there; by these presents we command you to repair to those regions of the said Indies, such as the islands of Hispaniola, Cuba, San Juan, and Jamaica as well as to the mainland; and you shall advise, inform, and give your opinion to the pious Jeronymite fathers whom we despatch to effect the reformation of the Indies, and to other persons who may assist them in this, concerning everything which touches the liberty, good treatment and welfare of the souls and bodies of the said Indians in the said islands and mainland; and that you shall write to us giving information concerning everything that may be done or should be done in the said islands; and that you shall do everything required for our Lord's service; for all of which we give you full power, with all its casualties, dependencies, emergencies, annexes, and connexes; and we command our Admiral and appellate judges and all other justices whatsoever of the said Islands and Tierrafirma that they protect you and cause this power to be protected and that they shall not oppose or go contrary to its form and tenor nor consent that such be done at any time or in any way under pain of our displeasure and of 10,000 maravedis for each person who may act to the contrary."
"Done at Madrid the 17th day of September in the year 1516 F. Cardinalis, Adrianus Ambasiator--By command of the Queen and the King her son, our sovereigns, the governors in their name. George de Baracaldo."