Musto is both an Italian and English surname (from different sources) and can refer to:
People with the surname
Adrian Musto, Italian director of photography
Alissa Musto, American singer and pianist
Arnold Musto (born 1883), British civil engineer who designed the Sukkur Barrage
Biagio Musto, bishop of Sora-Aquino-Pontecorvo (1952-1971) Franklyn Musto, English athlete at the 1964 Olympics Glenn Musto, singer-songwriter of pop band College Fall Keith Musto, British sailor at the 1964 Olympics. Manuel Musto, Argentinian impressionist painter Matthew Musto, known as Blackbear, American hip-hop artist Michael Musto, Italian-American writer Raphael J. Musto or Ray Musto, American politician from Pennsylvania Tony Musto (1915-1994), Italian-American heavyweight boxer William Musto, politician from New Jersey