This is a list of high school athletic conferences in the Central Region of Ohio, as defined by the OHSAA. Because the names of localities and their corresponding high schools do not always match and because there is often a possibility of ambiguity with respect to either the name of a locality or the name of a high school, the following table gives both in every case, with the locality name first, in plain type, and the high school name second in boldface type. The school's team nickname is given last.
Central Buckeye League
Columbus School for Girls Unicorns (2023-) Bexley Lions (2023-) Whitehall-Yearling Rams (2023-) Delaware Buckeye Valley Barons (2023-) Gahanna Columbus Academy Vikings (2023-) Grandview Heights Bobcats (2023-) Columbus Bishop Ready Silver Knights (2023-) Worthington Christian Warriors (2023-)
Future Members
Columbus Franklin Heights Falcons (2024-2025) (Non-football), (2025-) (All Sports)
Central Catholic League
Columbus Bishop Hartley Hawks (1957-) Columbus Bishop Watterson Eagles (1955-) Columbus St. Charles Cardinals (1923-) Columbus St. Francis DeSales Stallions (1960-)
Former members
Columbus Holy Family Golden Flashes (1928–60) Columbus Holy Rosary Ramblers (1928–66, consolidated into Father Wehrle) Newark Catholic Green Wave (1928-53 as St. Francis, 1991-2003) Columbus St. Mary Rams (1928–66, consolidated into Father Wehrle) Zanesville St. Nicholas Flyers (1928–50, consolidated into Bishop Rosecrans) Zanesville St. Thomas Aquinas Irish (1928–44, 1946–50, consolidated into Bishop Rosecrans) Mount Vernon St. Vincent De Paul Blue Streaks (1928–53) Zanesville Bishop Rosecrans Bishops (1950–77, 1979-2007) Springfield Catholic Central Fighting Irish (1951–53) Lancaster St. Mary Saints (1951–53) Marion St. Mary Fighting Irish (1951–53) New Lexington St. Aloysius Blue Knights (1955-1969) Columbus Father Wehrle Wolverines (1966–91, school closed) Columbus Worthington Christian High School Warriors (2007–13) Columbus Columbus School for Girls Unicorns (1988-2019, left for the Mid-State League) Columbus Bishop Ready Silver Knights (1960-2023, to Central Buckeye League)
Columbus City League
North Division
Columbus Beechcroft Cougars (1976-) Columbus Centennial Stars (1976-) Columbus East Tigers (1924-) Columbus Linden McKinley Panthers (1928-) Columbus North International Lions (2010-) Columbus Mifflin Punchers (1973-) Columbus Northland Vikings (1965-) Columbus Whetstone Braves (1961-)
South Division
Columbus Africentric Nubians (1999-) Columbus Briggs Bruins (1962-) Columbus Eastmoor Academy Warriors (1956-) Columbus Independence 76ers (1976-) Columbus Marion-Franklin Red Devils (1958-) Columbus South Bulldogs (1922-) Columbus Walnut Ridge Scots (1961-) Columbus West Cowboys (1922-)
Former members
Columbus Central Pirates (1922-1982) Columbus North Polar Bears (1924-1979) Columbus Mohawk Indians (1967–1978) Columbus Brookhaven Bearcats (1963-2014) Columbus Aquinas College Terriers (1922-1965)
Independents
Former Members
Powell Village Academy Griffins (School closed in 2019)
Knox-Morrow Athletic Conference
Started in 2017-18, the league was founded by members of the Mid-Ohio Athletic Conference's Blue Division.
Cardington-Lincoln Pirates (2017-) Centerburg Trojans (2017-) Danville Blue Devils (2017-) Howard East Knox Bulldogs (2017-) Fredericktown Freddies (2017-) Sparta Highland Fighting Scots (2017-) Mount Gilead Indians (2017-) Galion Northmor Golden Knights (2017-)
Licking County League
The league has two incarnations, the first lasting from 1927 to 1991. The second incarnation began 23 years later after travel and budget concerns brought together the ten schools that had made up league membership until 1986. The league is split into two divisions - Buckeye and Cardinal divisions.
Buckeye
Granville Blue Aces (1927-1950, 1963-1991, 2013-) Colors: Blue and White
Zanesville Blue Devils (2020-) Colors: Blue and White
Pataskala Licking Heights Hornets (1927-1983, 2013-, changed name from Summit Station 1958) Colors: Maroon and Gold Newark Licking Valley Panthers (1959-1991, 2013-) Colors: Red, White and Blue Pataskala Watkins Memorial Warriors (1955-1991, 2013-) Colors: Black and Gold