As _Tobacco_ is hot, dry, unctuous, and penetrating; it must, on account of these Qualities, soon take Flame: And, as it is possessed of an highly narcotic Quality, it, by its narcotic Sulphur, stupifies those who use it, corrupts the Temperature of the Brain, and destroys its Tone; whereas, the moderate Smoaking of _Marjoram_, _Betony_, _Rosemary_, _Amber_, and other Substances of a like Nature, would eliminate the Phlegm more safely, and without producing any of these ill Consequences. This narcotic Quality of _Tobacco_, is the Reason why great Smoakers are, during the whole of their Lives, afflicted with a continual Spitting, as I have observed in _Histor. Pompinellæ Class. secund. Quadripartit._ Though by the frequent Use of _Tobacco_, a large Quantity of Phlegm is eliminated from the Brain; this Plant is not, therefore, a peculiar Specific, adapted to that Organ: For, on the contrary, since it manifestly abounds with a narcotic Sulphur, it is highly injurious, not only to the Nerves, but also to the whole Substance of the Brain. Hence, as I observed before, many Users of _Tobacco_, not only have their olfactory Nerves so injured by its narcotic Sulphur, as to lose the Sense of Smelling, but are also observed not to have a very exquisite Taste, the fourth and seventh Pairs of Nerves being affected. Persons of this Kind are also observed to be fond of Malt Liquors, and to complain of a languid Appetite; because the sixth Pair of Nerves, which descends into the Stomach, is stupified by the narcotic Sulphur of the _Tobacco_: It is, therefore, absurd to maintain, that _Tobacco_ is of a cephalic Quality, and peculiarly adapted to the Disorders of the Head, since it is so unfriendly to the Nerves as to produce a Stupor in them. It is more reasonable to argue thus: _Tobacco_ is hot, consists of very subtle Parts, and is highly penetrating; therefore, being at the same Time narcotic, it will prove the more hurtful, the more penetrating it is; because the narcotic Quality of _Tobacco_, which is otherwise slow, like that of _Opium_, or _Hemlock_, is, by its other Qualities, exalted, and put in Action; or, to speak my Sentiments more freely, by means of the Acrimony ascribed to its Salt, whether fixed or volatile, the narcotic Sulphur is conveyed in its full Strength to the Nerves of the Head. That this Sulphur remains pretty long intire, even in a living Person, is sufficiently evinced, by that Saffron-coloured Liquor, smelling like _Tobacco_, which was discharged from the Nostrils of _Heurnius_, next Day after the Abuse of a Decoction of _Tobacco_ and _Camomile_ Flowers. I would not have any one imagine, that as soon as he lays by his Pipe, his Brain is no longer heated by the Smoak, which, for two or three Days after, he smells, or expires, when he sneezes. Thus, this narcotic, unctuous, and strong-smelled Sulphur, adhering to the Membranes, Ventricles, Gyrations, or other latent Passages of the Brain, and being left alone without either Smoak or Heat, gradually and insensibly corrupts the whole Mass of the Brain, by which Means _Tobacco_-Smoakers are obliged to spit and expectorate continually. When the Brain is thus weakened by the copious Spitting excited by the narcotic Sulphur, neither the _Tonsils_ nor the _Thymus_, which are destined for imbibing the natural excrementitious Humours of the Brain, are any longer fit for that Purpose. When such an Accident happens, the _Tobacco_-Smoaker begins to yawn, to have a hoarse and shrill Voice, and a stinking Breath, like those labouring under a _Lues Venerea_.