Silvestro is both a surname and a masculine Italian given name. Notable people with the name include:
Surname: Alex Silvestro (born 1988), American football player Chris Silvestro (born 1979), Scottish footballer Jim Silvestro (born 1963), Australian rules footballer Milo Silvestro, Italian musician, and lead singer of American heavy metal band Fear Factory René De Silvestro (born 1996), Italian para alpine skier
Given name: Silvestro Aldobrandini (1500–1558), Italian lawyer Silvestro de Buoni (died 1484), Italian Renaissance painter Silvestro Chiesa (died 1657), Italian Baroque painter Silvestro Durante (died 1672), Italian Baroque composer Silvestro Ganassi dal Fontego (born 1492), Italian musician Silvestro de' Gigli (died 1521), Italian Roman Catholic bishop Silvestro Lega (1826–1895), Italian painter Sylvestro "Pedro" Morales (18??–1???), Mexican bandit Silvestro Palma (1754–1834), Italian composer Silvestro Valiero (1630–1700), Doge of Venice