The 2022 Tel Aviv Open (also known as the 2022 Tel Aviv Watergen Open for sponsorship purposes) was a tennis tournament to be played on indoor hard courts. It was the inaugural edition of the Tel Aviv Open at the ATP Tour level since 1996, and part of the ATP Tour 250 series of the 2022 ATP Tour. It was played at Expo Tel Aviv in Tel Aviv, Israel, from 26 September to 2 October 2022.
The event was primarily organized due to the cancellation of tournaments in China during the 2022 season because of the ongoing COVID-19 pandemic.
Champions
Singles
Novak Djokovic def. Marin Čilić, 6–3, 6–4
It was Djokovic's 3rd title of the year and the 89th of his career.
Doubles
Rohan Bopanna / Matwé Middelkoop def. Santiago González / Andrés Molteni, 6–2, 6–4
Singles main-draw entrants
Seeds
1 Rankings are as of 19 September 2022.
Other entrants
The following players received wildcards into the main draw: Hamad Međedović Yshai Oliel Dominic Thiem
The following players received entry from the qualifying draw: Liam Broady Marius Copil Cem İlkel Edan Leshem
The following player received entry as a lucky loser: Vasek Pospisil
Withdrawals
Benjamin Bonzi → replaced by Hugo Grenier
Karen Khachanov → replaced by J. J. Wolf
Alex Molčan → replaced by Tomás Martín Etcheverry
Tommy Paul → replaced by Constant Lestienne
Albert Ramos Viñolas → replaced by Vasek Pospisil
Doubles main-draw entrants
Seeds
1 Rankings are as of 19 September 2022.
Other entrants
The following pairs received wildcards into the doubles main draw: Daniel Cukierman / Edan Leshem Hamad Međedović / Yshai Oliel
The following pair received entry as alternates: Marco Bortolotti / Sergio Martos Gornés
Withdrawals
Benjamin Bonzi / Arthur Rinderknech → replaced by Marco Bortolotti / Sergio Martos Gornés Tomás Martín Etcheverry / Albert Ramos Viñolas → replaced by Novak Djokovic / Jonathan Erlich