Nikola Mutafchiev () (10 August 1904 in Stara Zagora – 24 March 1963) was a Bulgarian footballer who played as a forward for Levski Sofia and Bulgaria during the 1920s. His elder brother Dimitar Mutafchiev also was a footballer.
Career
For six seasons from 1921 to 1927, Mutafchiev scored 50 goals in 52 games for Levski.
He played for the national team in the Bulgaria's first international match against Austria in Vienna on 21 May 1924. Mutafchiev also participated at the 1924 Summer Olympics. On 10 April 1925, he became the first player to score for Bulgaria in a 2–1 friendly loss against Turkey.