From this manner of regarding the influence of the black blood upon the different parts of the body, it appears that death is very soon the result of its circulation in the arteries. Nevertheless, certain organic defects have sometimes prolonged after birth, the mixture of the two sorts of blood, a mixture which is known to be made in the fœtus. Such was the malconformation mentioned by Sandeford, in a child, the aorta of which arose by a branch from each of the ventricles. Such also appears, at first sight, to be the opening of the foramen ovale in the adult.

We shall remark, however, that the existence of this foramen, does not suppose the passage of the black blood into the red-blooded auricle, as is generally believed. For the two semi-lunar valves, between which it is situated when met with after birth, are necessarily applied to each other by the pressure which the blood contained in the auricles, exercises upon them, when these cavities are simultaneously contracted. The foramen must be at such time shut, and its obliteration much more exact, than that of the opening of the ventricles, by the mitral and tricuspid valves, or that of the aorta and the pulmonary artery, by the sigmoid valves. With all this, the foramen ovale is actually very often found open in the subject, and when not so, nothing is easier than to destroy the species of adhesion which is contracted by the two valves which close it. This may be done with the handle of a scalpel, without any solution of continuity, the parts appear to be unglued.

Physiological Researches on Life and Death — Part 204

The oval hole when in this way artificially made, presents the same disposition, with that which is sometimes exemplified in the carcase. Now if this disposition be examined, it will be seen that when the auricles contract, the blood must make an obstacle to itself, and that it cannot pass from one into the other of these cavities. It is an easy thing to be convinced of the mechanism of which I speak, by means of two injections of a different colour, made at the same time from both sides of the heart, from the vena cava, and the pulmonary veins.

Physiological Researches on Life and Death — Part 204

From what we have said of the influence, which is exercised by the movement and the different principles of the blood, it is evident that the death of the white organs must be different from that of the red ones. Asphyxia can hardly reach them, but of the manner in which they die I confess that I know but little.

Physiological Researches on Life and Death — Part 204