They set sail at the end of February, and on August 10 dropped anchor in the Tagus. Charlevoix remarks that "this part of the journey was not long," though it was nearly six months in duration. The prince cardinal who was at that time Viceroy of Portugal showered honors upon them, and made them his guests in the royal palace for an entire month. They then visited the principal cities of Portugal. Nothing was too much for them in the way of honor and even in the way of money. Finally they were conducted to Madrid and had a public audience with Philip II, to whom they presented their credentials and offered the presents of the Christians of Japan and their expression of gratitude for all that his majesty had done for the infant Church of their country. Philip is said to have embraced them affectionately, assuring them of the great regard he had for the kings whom they represented. The Queen Maria put her carriages at their disposal, and on the following day they were conducted to the Escorial where they received the congratulations of the princes and grandees of Spain. The French ambassador also paid them a ceremonious visit. Even the king himself called upon them and had a vessel equipped at Alicante to conduct them to Italy. They left Madrid on November 26, and were received with almost royal honors in every city on their way. It was already January, 1585, when they left Spain. The Mediterranean treated them badly; and it was only in the month of March that they stepped ashore at Leghorn, amid the salvos of artillery from the fort. The carriages of the grand duke carried them on their journey to Pisa. There the prince and all his court were waiting to receive them, and led them to the palace, where a splendid banquet was prepared, after which Pietro de' Medici and the grand duke came to pay them their respects.
They saw the carnival at Pisa, and then journeyed on to Florence, where the papal nuncio and the cardinal archbishop, who was afterwards Pope Leo XI, bade them welcome. From there they passed to Siena, where, as guests of the Pope, they were met at the frontier by two hundred arquebusiers sent by the vice-legate of Viterbo to show them special honor. Gregory XIII was then on the Pontifical throne; and feeling that his end was approaching, he sent a company of light horse to hasten their coming. It was Friday, March 20, 1585, when they entered Rome, and their first visit was to Father Aquaviva, who was then General of the Society. He led them to the church, where a Te Deum was sung; and on the following day the Pope held a consistory which ordered that the envoys should be regarded as royal ambassadors; that their reception should be as splendid as possible; and that their first audience should be at the full consistory in the papal palace.