The 2021 Ole Miss Rebels football team represented the University of Mississippi in the 2021 NCAA Division I FBS football season. The Rebels played their home games at Vaught–Hemingway Stadium in Oxford, Mississippi, and competed in the Western Division of the Southeastern Conference (SEC). They were led by second-year head coach Lane Kiffin. This was the first season in program history that the team finished the regular season with 10 wins.
SEC Media Days
In the preseason media poll, Ole Miss was predicted to finish 4th in the West Division.
Regular season
Schedule
Schedule Source:
Rankings
Game summaries
Vs. Louisville
No. 17 (FCS) Austin Peay
Tulane
At No. 1 Alabama
No. 13 Arkansas
At Tennessee
LSU
At No. 18 Auburn
Liberty
No. 11 Texas A&M
Vanderbilt
At Mississippi State
Vs. No. 7 Baylor (Sugar Bowl)