Memnon, a brother of Mentor the Rhodian, with the satraps Spithrida´tes and Arsi´tes, commanded the Persians in Asia Minor. Their first collision with Alexander was in the attempt to prevent his passage of the Grani´cus, a little Mysian river which flows into the Propon´tis. They were totally defeated, and Alexander, advancing southward, subdued, or rather liberated all the cities of the western coast without long delay. Halicarnas´sus, under the command of Memnon, made an obstinate resistance, and it was only at the end of autumn that it surrendered. Memnon then resolved to carry the war into Greece. He gathered a large fleet and captured many islands in the Ægean; but his death at Mytile´ne relieved Alexander of the most able of his opponents.
=81.= The king of Macedon wintered at Gor´dium, where he cut or untied the celebrated knot, which an ancient prophecy had declared could never be loosened except by the conqueror of Asia. With fresh reinforcements from Greece, he commenced his second campaign, in the spring of 333, by marching through Cappadocia and Cilicia to the gates of Syria. Darius met him, in the narrow plain of Issus, with an army of half a million men. Hemmed in between the mountains, the river, and the sea, the Persian horsemen could not act, and their immense numbers were rather an incumbrance than an advantage. Darius was defeated and fled across the Euphrates. His mother, wife, and children fell into the hands of the conqueror, who treated them with the utmost delicacy and respect.
=82.= B. C. 333-331. The conquests of Syria, Phœnicia, and Egypt, which Alexander now accomplished in less than two years, will be described in the Macedonian history. In the spring of 331, he retraced his triumphant march through Syria, crossed the Euphrates at Thapsacus, traversed Mesopotamia, and met Darius again on the great Assyrian plain east of the Tigris. The Persian king had spent the twenty months which had intervened since the battle of Issus in mustering the entire force of his empire. The ground was carefully selected as most favorable to the movements of cavalry, and as giving him the full advantage of his superior numbers. A large space was leveled and hardened with rollers for the evolutions of the scythe-armed chariots. An important part of the infantry was formed of the brave and hardy mountaineers of Afghanistan, Bokhara, Khiva, and Thibet; and the cavalry, of the ancestors of the modern Kurds and Turcomans, a race always distinguished for bold and skillful horsemanship. A brigade of Greek auxiliaries was alone considered able to withstand the charge of Alexander’s phalanx. Altogether the forces of Darius numbered more than a million of men, and they surpassed all former general levies of the Persians in the efficient discipline which enabled them to act together as one body.