_Experiment No. 10._--A mouse-colored rabbit weighing 1,927.8 grams was fed February 18, 1906, at 2.26 p.m., with a concentrated aqueous extract of 250 grams of fresh _Astragalus mollissimus_ collected in September, 1905, and preserved in chloroform water. The temperature of this rabbit was 102.6°F. The fluid given was 40 c.c. At 2.45 p.m. the rabbit urinated and at 2.57 p.m. was dull and the respiration became rapid. The animal then aborted and had three young, two of which showed some movement after birth, but were apparently premature.
On February 23 the temperature of this rabbit was 102.9°F. at 1.40 p. m. She was then fed with the same amount of the extract as before. At 2.16 p.m. she lay down and became much duller; left ear fallen to side. At 3.30 p.m. the rabbit was unable to stand. The pupil of the eye exposed to the light was dilated. The animal died without a struggle. The stomach contained much bloody mucus. In the dependent portion of the stomach near the cardiac end were marked petechiæ in the walls, with bright-red blood in the stomach itself. The heart was relaxed. The intestines showed nothing abnormal. The dural vessels of the brain were dilated; there was a clot on the dura over the fourth ventricle. Spinal cord and kidneys normal, the capsules not adhering. Weight, 1,786 grams at death.

_Experiment No. 11._--On March 1, 1906, a rabbit weighing 2,126.2 grams was fed with a concentrated aqueous extract of 250 grams of the fresh _Aragallus lamberti_ preserved in chloroform water. On March 5 this dose was repeated, 37.5 c.c. of the fluid being used. March 6 the rabbit weighed 1,956 grams; March 7, 1,913.6 grams; March 8, 1,828.5 grams; March 9, 1,701 grams; March 12, 1,672.6 grams; March 14, 1,644.3 grams.

_Experiment No. 12._ January 19, 1906, a concentrated aqueous extract of 500 grams of the fresh _Aragallus lamberti_ preserved with chloroform water was fed to a rabbit weighing 785 grams. The temperature at 12.10 p.m., the time of feeding, was 101.6°F. The temperature 1 hour and 43 minutes later was 94.6°F., and the animal died shortly after, showing the same condition as occurred after feeding extracts of _Astragalus mollissimus_.

[156] Compare Plönius, W., Beziehungen d. Geschwürs u. d. Erosionen d. Magens z. d. funktionell. Störungen u. Krankh. d. Darmes, Arch. f. Verdauungsk., vol. 13, pp. 180, 270, 1907, and Tixier, L., Anémies Exper. Conséc. aux Ulcér. du Pylore, Comp. Rend. Hebd. Soc. de Biol., vol. 62, p. 1041, 1907.





