Uruguay competed at the 1968 Summer Olympics in Mexico City, Mexico. 27 competitors, 21 men and 6 women, took part in 31 events in 8 sports.
Athletics
Albertino Etchechury
Armando González
Josefa Vicent
Boxing
Mario Benítez
Juan Carlos Rivero
Carlos Alberto Casal
Nolberto Freitas
Cycling
Five cyclists represented Uruguay in 1968.
Team time trial
Walter Garre
Luis Sosa
René Deceja
Jorge Jukich
1000m time trial
Luis Barruffa
Fencing
One fencer represented Uruguay in 1968.
Men's foil
Alberto Varela
Men's épée
Alberto Varela
Rowing
Emilio Ahlers
José Ahlers
Luis Colman
Esteban Masseilot
José Sigot
Sailing
Fernando Thode
Shooting
Three shooters, all men, represented Uruguay in 1968.