Hitherto Mary had not been worshipped; all prayers had been addressed to God and to Christ. The idea of approaching her in prayer appeared for the first time in a pamphlet entitled "On the Death of Mary," written about the end of the fourth century, and Gregory of Nazianz pictured Mary in Heaven, caring for the welfare of humanity. The fourth and fifth centuries produced the first hymns to the Virgin, written in Syriac; but orthodox bishops objected to her deification; St. Epiphanus (end of fourth century) said: "Let us honour Mary by all means, but let us worship only the Father, the Son and the Holy Ghost."
This was the position of the evangelical and historical Mary before the famous and decisive Council of Ephesus.
There is a very important fact which must not be overlooked. All the nations dwelling on the shores of the Mediterranean, Semites, and Egyptians, as well as Greeks and Romans, had been accustomed to the worship of female deities. In the minds of the ancient peoples, woman, the symbol of sex, had always been endowed with qualities of magic and mystery. There was something supernatural in her power of bringing forth a living specimen of the race, and in all cults the maternal woman occupied a very important position. Had Christianity suddenly destroyed this ancient and natural need? We know that the Church had assimilated a great number of antique superstitions; nor were the female deities sacrificed. The great Asiatic Mothers had not been forgotten; the very ancient Babylonian Istar (Astarte), Rhea Kybele of Asia Minor, and above all the Egyptian Isis, still lived in the heart of man,--subconsciously, probably--as lofty, sacred memories, but nevertheless influencing his life. The Egyptian Isis with Horus in her lap is the direct model of the Madonna with the Child. She represented earth, bringing forth fruit without fertilisation. "This religious custom (the worship of Isis)," says Flinders Petrie, "exerted a powerful influence on nascent Christianity. It is not too much to say that without the Egyptians we should have had no Madonna in our creed. The cult of Isis was widely spread at the time of the first emperors, when it was fashionable all over the Roman Empire; when later on it merged into that other great religious movement, and fashion and conviction could be combined, its triumph was assured."