Miller–Seabaugh House and Dr. Seabaugh Office Building is a historic home and office building located at Millersville, Cape Girardeau County, Missouri. The house was built about 1883, and is a -story, irregular plan brick dwelling. It features arched windows and corbelling along the eaves. The doctor's office was moved to the property about 1911, and is a one-room frame building on a sandstone foundation.
It was listed on the National Register of Historic Places in 1996.