The 2022 Monterrey Challenger was a professional tennis tournament played on hard courts. It was the twelfth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Monterrey, Mexico from 7 to 13 March 2022.
Singles main draw entrants
Seeds
1 Rankings are as of 28 February 2022.
Other entrants
The following players received wildcards into the singles main draw: Milledge Cossu Ryan Harrison Alex Hernández
The following players received entry into the singles main draw using protected rankings: Ulises Blanch Li Zhe Go Soeda Rubin Statham
The following players received entry from the qualifying draw: William Blumberg Strong Kirchheimer Aleksandar Kovacevic Naoki Nakagawa Sho Shimabukuro Evan Zhu
Champions
Singles
Fernando Verdasco def. Prajnesh Gunneswaran 4–6, 6–3, 7–6(7–3).
Doubles
Hans Hach Verdugo / Austin Krajicek def. Robert Galloway / John-Patrick Smith 6–0, 6–3.