Lofton is a surname and occasionally a given name. Notable people with the name include:
Surname
Cirroc Lofton (born 1978), American actor
Chris Lofton (born 1986), American basketball player
Curtis Lofton (born 1986), American football linebacker
David Lofton (born 1984), American football safety
Eric Lofton (born 1993), Canadian football offensive lineman
James Lofton (born 1956), former American Football wide receiver and coach
James Lofton (baseball) (born 1974), former Major League Baseball shortstop
John Lofton (1941–2014), American political commentator
Kenneth Lofton Jr. (born 2002), American basketball player
Kenny Lofton (born 1967), Major League Baseball outfielder
Oscar Lofton (born 1938), American football player and coach
Ramona Lofton (born 1950), nicknamed Sapphire African-American author and performance poet Saab Lofton, American author, cartoonist and radio personality Steve Lofton (born 1968), American football cornerback Tricky Lofton (born 1930), American jazz trombonist Willie Lofton (1897 - 1956 or c. 1962), American Blues musician