The 2019 Pittsburgh Pirates season was the franchise's 138th season overall, 133rd season as a member of the National League, and 19th season at PNC Park. The Pirates were eliminated from postseason contention after a 14-1 loss to the Cubs on September 14, 2019. Manager Clint Hurdle was fired an hour before the start of the final game of the 2019 season. Tom Prince, the Pirates' bench coach, managed the team for the season finale.
Season standings
National League Central
National League playoff standings
Record vs. opponents
Detailed records
Game log
|-style="background:#fbb" |1||March 28||@ Reds || 3–5 || Duke (1–0) || Taillon (0–1) || Hernandez (1) || 44,049 || 0–1 || L1 |-style="text-align:center; background:#bbb;" |—||March 30||@ Reds || colspan="7" |PPD, RAIN; rescheduled for May 27 |-style="background:#bfb" |2||March 31||@ Reds || 5–0 || Williams (1–0) || Gray (0–1) || — || 18,737 || 1–1 || W1 |-
|-style="background:#fbb" |3||April 1||Cardinals || 5–6 (11) || Hicks (1–1) || Brault (0–1) || Gant (1) || 37,336 || 1–2 || L1 |-style="background:#fbb" |4||April 3||Cardinals || 4–5 (10) || Gant (2–0) || Burdi (0–1) || Hudson (1) || 23,954 || 1–3 || L2 |-style="background:#bfb" |5||April 4||Reds || 2–0 || Kingham (1–0) || Hernandez (0–1) || Vázquez (1) || 8,523 || 2–3 || W1 |-style="background:#bfb" |6||April 5||Reds || 2–0 || Musgrove (1–0) || Gray (0–2) || Vázquez (2) || 12,497 || 3–3 || W2 |-style="background:#bfb" |7||April 6||Reds || 6–5 (10) || Liriano (1–0) || Iglesias (0–2) || — || 15,798 || 4–3 || W3 |-style="background:#bfb" |8||April 7||Reds || 7–5 || Archer (1–0) || DeSclafani (0–1) || Rodríguez (1) || 14,750 || 5–3 || W4 |-style="background:#fbb" |9||April 8||@ Cubs || 0–10 || Brach (1–0) || Taillon (0–2) || — || 40,692 || 5–4 || L1 |-style="background:#bfb" |10||April 10||@ Cubs || 5–2 ||Lyles (1–0) || Darvish (0–2) || Vázquez (3) || 32,798 || 6–4 || W1 |-style="background:#fbb" |11||April 11||@ Cubs || 0–2 ||Quintana (1–1) ||Musgrove (1–1) || Strop (1) || 31,906 || 6–5 || L1 |-style="background:#bfb" |12||April 12||@ Nationals || 6–3 (10) || Burdi (1–1) || Grace (0–1) || Vázquez (4) || 27,084 || 7–5 || W1 |-style="background:#fbb" |13||April 13||@ Nationals || 2–3 || Suero (1–0) || Rodríguez (0–1) || Doolittle (1) || 32,103 || 7–6 || L1 |-style="background:#bfb" |14||April 14||@ Nationals || 4–3 || Vázquez (1–0) || Suero (1–1) || — || 22,347 || 8–6 || W1 |-style="background:#bfb" |15||April 16||@ Tigers || 5–3 (10) || Kela (1–0) || Greene (0–1) || Kingham (1) || 13,251 ||9–6|| W2 |-style="background:#bfb" |16||April 17||@ Tigers || 3–2 (10) || Burdi (2–1) || Farmer (1–1) || Vázquez (5) || 12,994 || 10–6 || W3 |-style="background:#bfb" |17||April 19||Giants || 4–1 || Lyles (2–0) || Bumgarner (1–3) || Vázquez (6) || 15,049 || 11–6 || W4 |-style="background:#bfb" |18||April 20||Giants || 3–1 (5) || Taillon (1–2) || Holland (1–3) || — || 17,663 || 12–6 || W5 |-style="background:#fbb" |19||April 21||Giants || 2–3 || Rodríguez (3–2) || Archer (1–1) || Smith (5) || 12,396 || 12–7 || L1 |-style="background:#fbb" |20||April 22||Diamondbacks || 4–12 || Andriese (3–1) || Crick (0–1) || — || 9,233 || 12–8 || L2 |-style="background:#fbb" |21||April 23||Diamondbacks || 1–2 || Weaver (2–1) || Williams (1–1) || Holland (5) || 8,558 || 12–9 || L3 |-style="background:#fbb" |22||April 24||Diamondbacks || 2–11 || Kelly (2–2) || Lyles (2–1) || — || 9,450 || 12–10 || L4 |-style="background:#fbb" |23||April 25||Diamondbacks || 0–5 || Greinke (4–1) || Taillon (1–3) || — || 9,365 || 12–11 || L5 |-style="background:#fbb;” |24||April 26||@ Dodgers || 2–6 || Ryu (3–1) || Archer (1–2) || — || 50,748 || 12–12 || L6 |-style="background:#fbb" |25||April 27||@ Dodgers || 1–3 || Kershaw (1–0) || Musgrove (1–2) || Jansen (9) || 47,877 || 12–13 || L7 |-style="background:#fbb" |26||April 28||@ Dodgers || 6–7 || Urías (2–1) || Rodríguez (0–2) || Jansen (10) || 52,875 || 12–14 || L8 |-style="background:#bfb" |27||April 30||@ Rangers || 6–4 (11) || Crick (1–1) || Chavez (0–1) || Vázquez (7) || 18,641 || 13–14 || W1 |-