The Rue Mercière (Merchants Street in English) is a medieval street in Strasbourg, France. It runs for about and connects the Rue du Vieux-Marchè-aux-Poissons in the west to the Place de la Cathédrale, surrounding Strasbourg Cathedral, in the east. It is bisected by the Rue du Fossè des Tailleurs to the north and the Rue du Vieil Hôpital to the south.
The street is a popular viewing point from which to photograph the cathedral:
In 1922, Hegemann and Peets wrote:
At the corner of the Place de la Cathedral and the Rue Mercière stands the Pharmacie du Cerf. Established in 1268, it is the oldest pharmacy in France.
In 1995, Strasbourg City Council decided to add two-language signs to around fifty streets in the city, including the Rue Mercière. Its other name became Krämergass.