Such was the empire inherited by Sargon's son, Sennacherib. Not content, he would go farther afield to make a conquest which has never remained long in the hands of an Asiatic power. It was not only lust of loot, however, which now urged Assyria towards Egypt. The Great Kings had long found their influence counteracted in southern Syria by that of the Pharaohs. Princes of both Hebrew states, of the Phoenician and the Philistine cities and even of Damascus, had all relied at one time or another on Egypt, and behind their combinations for defence and their individual revolts Assyria had felt the power on the Nile. The latter generally did no more in the event to save its friends than it had done for Israel when Shalmaneser IV beleaguered, and Sargon took and garrisoned, Samaria; but even ignorant hopes and empty promises of help cause constant unrest. Therefore Sennacherib, after drastic chastisement of the southern states in 701 (both Tyre and Jerusalem, however, kept him outside their walls), and a long tussle with Chaldaean Babylon, was impelled to set out in the last year, or last but one, of his reign for Egypt. In southern Palestine he was as successful as before, but, thereafter, some signal disaster befell him. Probably an epidemic pestilence overtook his army when not far across the frontier, and he returned to Assyria only to be murdered.
He bequeathed the venture to the son who, after defeating his parricide brothers, secured his throne and reigned eleven years under a name which it has been agreed to write Esarhaddon. So soon as movements in Urartu and south-western Asia Minor had been suppressed, and, more important, Babylon, which his father had dishonoured, was appeased, Esarhaddon took up the incomplete conquest. Egypt, then in the hands of an alien dynasty from the Upper Nile and divided against itself, gave him little trouble at first. In his second expedition (670) he reached Memphis itself, carried it by assault, and drove the Cushite Tirhakah past Thebes to the Cataracts. The Assyrian proclaimed Egypt his territory and spread the net of Ninevite bureaucracy over it as far south as the Thebaid; but neither he nor his successors cared to assume the style and titles of the Pharaohs, as Persians and Greeks, wiser in their generations, would do later on. Presently trouble at home, excited by a son rebelling after the immemorial practice of the east, recalled Esarhaddon to Assyria; Tirhakah moved up again from the south; the Great King returned to meet him and died on the march.