Raymond Leo Burke (born June 30, 1948) is an American prelate of the Catholic Church. He is a cardinal, and the patron of the Sovereign Military Order of Malta. He led the Archdiocese of St. Louis from 2004 to 2008 and the Diocese of La Crosse from 1995 to 2004.
From June 2008 to November 2014, he was the prefect of the Supreme Tribunal of the Apostolic Signatura. He was born in Richland Center, Wisconsin.
During the COVID-19 pandemic, Burke became known for being against the COVID-19 vaccine. In August 2021, he was hospitalized under critical condition after being diagnosed with COVID-19.