His eyesight being now restored, he began work again as soon as he arrived. This period, however, was not a pleasant one: to begin with, he obtained in the study of Ascidia a result which differed considerably from that obtained by Kovalevsky,[11] and this scientific controversy grieved and preoccupied them both. Besides, Elie's nerves suffered from his constant anxiety about his eyes, the tropical heat and the noisy life of Naples. Incessant serenades used to keep him awake at night, and, on one occasion, his exasperation reached such a point that he poured a bucket of water over the head of some persistent musicians. Tired with all these things, he left Naples for Trieste, where he carried out successful researches into the transformations of Echinodermata, from the point of view of Comparative Embryology and genetic connections between inferior animals.

[11] The latter affirmed that the nervous system of Ascidia originated from the upper layer, whilst Elie believed that it was the lower layer which gave birth to it. It was Kovalevsky who was right, as Elie himself declared later.

Life of Elie Metchnikoff, 1845-1916 — Part 44

Having obtained results which interested him, he returned to Russia and joined the B. family in the country, near Moscow. Their young friend Mlle. Fédorovitch, whom he had already met in Petersburg, was staying with them, and she and Elie became very good friends. His affection for the B. children led him to ponder over general educational questions. He was struck for the first time by the lack of harmony in human nature, which was due, he thought, to the considerable difference between the organism of the child and that of the adult, a difference which does not exist in animals to the same degree.[12] As soon as he returned to Petersburg he tried to study this subject, and made comparisons between the brain of a man and that of a dog at various ages, but without result.

Life of Elie Metchnikoff, 1845-1916 — Part 44

[12] He ultimately developed these considerations in a paper entitled _Education from an Anthropological Point of View_, of which mention will be made hereafter.

Life of Elie Metchnikoff, 1845-1916 — Part 44

He was not long in realising that the conditions of work in his new post were extremely unsatisfactory. He had no proper laboratory and had to work between two specimen cases in a non-heated zoological museum; there was no room for practical work. All his enthusiasm, all his aspirations towards scientific activity and rational teaching struck against indifference, lack of organisation, and lack of means. He protested with his usual vehemence, but could obtain nothing; being equally unable to adapt himself to his uncongenial surroundings, he found himself getting more and more discontented and unnerved. Moreover, his everyday life was most uncomfortable, for he wished to do without servants, on principle and in order to economise, and to do his household work himself; but he soon tired of taking the necessary care of his rooms, which became a regular chaos. He left off preparing his own meals and went out for them to an inferior restaurant in the neighbourhood. Yet, in spite of all his efforts and privations, he never seemed to make both ends meet. He resigned himself to giving lessons at the School of Mines in order to increase his resources; the school was a long way off, he had to walk the distance in the coldest weather in order to lecture to students who did not interest him. The work wearied him without giving him any moral compensation. Altogether, the life in Petersburg, on which he had founded great hopes, brought him nothing but disappointments and made him become more and more pessimistic and misanthropical.