U.S. President Donald Trump and Russian President Vladimir Putin sat down Monday at their Helsinki summit with an array of complex issues to discuss.

Whether the leaders of the world's two foremost nuclear superpowers would resolve any of their disagreements was an open question as they began their first extensive face-to-face talks since Trump assumed power nearly 18 months ago. Trump is the fourth U.S. president Putin has engaged with.

At Trump-Putin Summit, Issues Are Complex

It was not known which issues might draw particular attention as they first talk alone, accompanied only by their translators, and later over lunch with additional key aides. Here are some of the contentious issues that have soured relations between the United States and Russia:

At Trump-Putin Summit, Issues Are Complex

"President Obama lost Crimea, because President Putin didn't respect President Obama," Trump said last month.

At Trump-Putin Summit, Issues Are Complex

Trump has said he will raise the election interference issue with Putin, but it is unclear how extensively he plans to press the Russian leader. Just hours before the summit, Trump said on Twitter, "Our relationship with Russia has NEVER been worse thanks to many years of U.S. foolishness and stupidity and now, the Rigged Witch Hunt!"

Our relationship with Russia has NEVER been worse thanks to many years of U.S. foolishness and stupidity and now, the Rigged Witch Hunt!