Recently, the National Centre for Disease Informatics and Research (NCDIR) and the Indian Council of Medical Research (ICMR) released a report that analyses the profile of cancer patients in India. The report considered only 6.1 lakh cases out of the total 13.3 lakh cancer cases that were registered in the 96 participating hospitals, due to quality and completeness of the data. According to the World Health Organization (WHO), the term ‘Cancer’ is used to refer to a large group of diseases that can affect any part of the body. It is defined by the rapid creation of abnormal cells which grow beyond their usual boundaries. It can then invade the adjoining parts of the body and spread to other organs. The spread of cancer to new parts of the body is known as metastasis, which is the primary cause of death from cancer. Cancers claimed the lives of 1 crore persons globally in 2020 In 2020 alone, nearly 10 million deaths or one crore deaths globally were because of cancer. Further, around 70% of deaths from cancer occur in low- and middle-income countries. In 2020 alone, lung cancer claimed the lives of over 18 lakh persons. The second most cause of cancer death was colon and rectum cancer which resulted in the death of 9.35 lakh persons followed by liver cancer that claimed the lives of 8.3 lakh persons. Stomach cancer resulted in the death of 7.69 lakh persons worldwide, and breast cancer caused 6.85 lakh deaths. Tobacco use, high Body Mass Index, alcohol consumption, lack of physical activity, and poor fruit and vegetable intake, are responsible for one in three deaths due to cancer. It can be acute (sudden onset), sub-acute (slow onset), or chronic (long period) and multifactorial in origin. Six site-specific cancers accounted for over one crore cancer cases reported in 2020 WHO had earlier projected that cancer rates may rise by at least 60% in the next two decades. In terms of the new cancer cases reported globally in 2020, the most common cancer was breast cancer. 22.6 lakh cases of breast cancer were reported followed by 22.1 lakh cases of lung cancer. About 19.3 lakh cases of colon and rectum cancer, 14.1 lakh cases of prostate cancer, 12 lakh cases of non-melanoma skin cancer and 10.9 lakh cases of stomach cancers were also reported. In other words, six site-specific cancers alone accounted for over one crore cancer cases reported in the year 2020 while according to the International Classification of Diseases for Oncology, there are more than 600 types of cancer. NCDIR-ICMR recently released a comprehensive report of anatomic site-wise cancers Recently, the National Centre for Disease Informatics and Research (NCDIR) and the Indian Council of Medical Research (ICMR) released ‘Clinicopathological Profile of Cancers in India: A report of the Hospital Based Cancer Registries, 2021’. The report gives a comprehensive overview of the distribution of cancer cases in India based on data from participating hospitals and cancers in sites associated with tobacco use. Furthermore, a detailed anatomic site-wise clinical description for eight systems/specific organs, viz; cancers of head and neck, gastrointestinal tract, lungs, gynaecological and breast, prostate, kidney and urinary bladder, brain and nervous system, and thyroid cancers have been covered in the report. The data is intended to help understand the gravity of the disease in the country and aid in decision-making, policy formulation, research, and improving cancer care. Cancer registries are maintained by countries and collate data on incidence, type, and mortality due to cancer in the country. In India, the National Cancer Registry Programme Report (NCRP) provides information on estimated incidence and mortality in India. For this report, data on cancer cases from 96 Hospital Based Cancer Registries under the National Cancer Registry Programme (NCRP) has been collected for the seven-year period from 2012 to 2019. The data pertains to all diagnosed and treated cases of confirmed malignancies reported to these centres across the country during this period. 13.9 lakh cases of Cancer are estimated in India in 2020 The report states that the estimate of cancer cases in the country is 13.9 lakhs as of 2020, up from 13.25 lakh cases in 2018. Projections suggest that the incidence of cases would increase by 13% to reach 15.7 lakh cases by 2025. For this report, the NCDIR considered only 6.1 lakh cases out of the total 13.3 lakh cancer cases that were registered in the 96 participating hospitals, due to the quality and completeness of the data. The proportion of all cancer cases is higher in males & most due to Tobacco usage The proportion of all cancer cases was higher in males with 3.19 lakh cases (52.4%) as compared to 2.9 lakh cases (47.4%) in females.