Woorara is a solid extract, black, resinous looking, soluble in water. We shall have occasion hereafter to advert to its chemical properties. Our attention will now be directed to its physiological effects when exerted on living animals. Woorara resembles venom in this, that it can be eaten, that is, taken into the digestive canal of man and other animals with impunity, whilst when introduced by puncture under the skin, or in any other part of the body, its absorption is invariably attended with fatal results in all animals. This fact we have repeatedly tested. The action of this poison is instantaneous, when it is injected directly into the blood vessels. A weak, watery solution thrown into the jugular vein of a dog or a rabbit, has always produced sudden death, the animal uttering no cry, nor manifesting any convulsive agitation. The effect on the whole organization is electric, and the vital functions are arrested as by lightning. When introduced under the skin in solution or in solid fragments, its poisonous action manifests itself more slowly, and the time is varied by the dose, the size of the animal, and its species. Other things being equal, birds die soonest, then the mammalia, and then reptiles; thus, with the same specimen, birds and mammalia die in a few minutes, whilst a reptile will survive for several hours. But death is invariably accompanied by similar, and very remarkable symptoms; in the first place, when pricked, the animal apparently feels nothing. If a bird, for example, it flies as usual, and at the end of a few seconds, when the woorara is very active, it drops dead without uttering a cry, or appearing to suffer; if it be a rabbit or a dog, it runs about as usual after the puncture, without any abnormal symptom, then, after some seconds, as if fatigued, it lies down, appears to sleep, its respiration stops, and life is terminated, without a groan or sign of pain. Rarely do we see even slight contraction of the sub-cutaneous muscles of the face and body.

On examining immediately after death, the bodies of { 79} animals thus poisoned, we have always observed phenomena which indicate a complete annihilation of all the properties of the nervous system. It is generally found that when death has been sudden, the nerves retain for some time the power of reaction under the influence of mechanical or chemical excitement; if a nerve of motion be excited, convulsions supervene in the muscles to which it leads; if the skin be pinched, it causes reflex motion. But none of these are observed after death by woorara. The nerves of the still warm animal, in whom life has been extinct but a minute, are inert as if it had been dead and cold for several hours.

New York Journal of Pharmacy, Volume 1 (of 3), 1852 — Part 66