Sandworm may refer to:
Living animals
Arenicola marina (lugworm), called "sandworm" in the UK
Alitta virens, formerly Nereis virens (king ragworm), called "sandworm" in the US Hookworm larvae which cause cutaneous larva migrans, called "sandworms" in the southern US
Fictional animals
Sandworm (Dune), from Frank Herbert's 1965 science fiction novel Dune and its derivative works. When Barbara and Adam Maitland die, they come across a sandworm creature that lives on the desert of Saturn in the 1988 Tim Burton film Beetlejuice.
Other
Sandworm (installation), an environmental art installation in the Wenduine Beach, Belgium created for the Beaufort Triennial of Contemporary Art Mongolian death worm, said to inhabit the Gobi Desert Sandworm, a hacker group within the GRU (G.U.), a foreign military intelligence agency of the Russian Federation Sandworm: A New Era of Cyberwar and the Hunt for the Kremlin's Most Dangerous Hackers (2019), a book about the group by Andy Greenberg