The 2010 season for began in January with the Tour Down Under and ended at the Giro di Lombardia. As a UCI ProTour team, they were automatically invited and obliged to attend every event in the ProTour. The season is the sixteenth for the unofficial Basque national team. The team's manager is former Euskadi rider Igor González de Galdeano, who is in his first year in the position after taking over from Miguel Madariaga.
A notable rider joining the team in 2010 is Romain Sicard, the reigning under-23 world champion. Sicard, from the French Basque Country, is only the second non-Spanish rider ever to join the team.
2010 roster
Ages as of January 1, 2010.
Riders who joined the team for the 2010 season
Riders who left the team during or after the 2009 season
One-day races
Spring classics
Fall races
Stage races
Grand Tours
As they did in 2009, Euskaltel declined invitation to the Giro d'Italia in 2010.
Tour de France
Sánchez was the leader of Euskaltel's squad for the Tour, with several Grand Tour veterans beside him, though the team held out some strong riders for the Vuelta a España later in the season. Their goals were a stage win and a high overall placing for Sánchez, who did not ride the Tour in 2009 but had finished seventh overall in 2008.
The squad, being largely composed of climbing specialists, was quiet through the flat stages in the Tour's first week. In stage 8, the race's first mountain stage, Sánchez made all the day's selections and finished at the head of the race, just missing out on a stage win as Andy Schleck pipped him in a two-up sprint. The result did, however, move Sánchez from 21st up to ninth in the overall standings. In stage 9, Sánchez responded to an attack from Schleck and Alberto Contador, briefly riding past them. The two in turn attacked past Sánchez and finished the stage over a minute ahead of him. Sánchez did, however, stay ahead of the other elite riders in the race, gaining a minute on them and moving up to third in the overall classification. In stage 12, Sánchez finished with the main group on the road for sixth on the day, losing ten seconds to Contador but maintaining third overall. In stage 14, after Contador and Schleck, the top two men in the overall standings, came to a bizarre seeming track stand in the stage's final kilometer, Sánchez and fourth place man Denis Menchov rode past them and gained 14 seconds back. The next day, Sánchez followed Contador when he controversially attacked past Schleck as the Luxembourger suffered a mechanical incident. Their group gained 39 seconds over Schleck, but since Menchov was also present, Sánchez's position was largely unchanged. In stage 17, Schleck and Contador again finished well ahead of the rest of the race's elite and decided the stage between themselves. Sánchez was fifth on the day and gained 8 seconds over Menchov in the fight for the bottom step of the podium, but had a lead of only 21 seconds with a long individual time trial (where Menchov is superior) looming. Sánchez indeed fell from the podium in the stage 19 time trial, ceding two minutes to his Russian rival. He still had a comfortable lead over Jurgen Van den Broeck in fifth, and held fourth place after the Tour's largely ceremonial final stage. Though the team did not win anything at the Tour, they did achieve their stated goal of obtaining a high placing for Sánchez. The squad finished eighth in the teams classification.
Vuelta a España
Antón was the team's leader at the Vuelta a España, heading a squad of climbing specialists. They were 13th in the stage 1 team time trial, finishing with six riders 27 seconds off the winning time set by . Antón was third in the first mountain stage two days later, entering the top ten overall at seventh with the result. Antón was the winner the next day in a hilly stage that ended with a short but nearly vertical climb to Valdepeñas de Jaén. He had started his attack on the wall at the finish early, and faded in sight of the line, but held off Vincenzo Nibali and Peter Velits to claim the day's honors. The result moved him into second overall, 10 seconds behind race leader Philippe Gilbert and tied with Joaquim Rodríguez in third.