In the vast storehouse of Nature the department most likely to furnish such antidotes is the vegetable kingdom. The untutored human mind has for centuries past intuitively clung to this idea, and sought among plants for remedies against the deadly ophidian poison. Hence the great number of vegetable antidotes that have from time to time been recommended and the efficacy of some of which at least has been confirmed by reliable observations. But the hint thus given to science was not taken. Instead of research being pushed on diligently in the only direction that promised any chance of success, it was cut short by the baneful method of experimenting on animals. When it had been demonstrated that a dog, a cat, or other animal, after having been saturated with snake-poison, did not recover after the administration of an alleged antidote, the illogical conclusion was drawn at once that it could not possibly be of any use to man, whilst, in reality, the only proof rendered by the experiment, if made properly, was that the respective antidote could not be relied on in treating animals of the class experimented on. That some of these despised antidotes are worth a little further investigation may, in the light of present experience as to the value of strychnine in snakebite, be inferred from the fact, that among them is the wood of _Strychnos Colubrina_, and also the well-known _Huang Noo_, a vegetable extract made from another variety of the Strychnos family, and largely used by the Chinese, whilst, according to a letter in the _Australasian Medical Gazette_, July, 1892, the principal ingredient of a strange compound used by the native snake doctors of Central America with much success is _Nux Vomica_.
It is superfluous to enter into a criticism of the treatment of snakebite until recently in vogue, for, with the exception of the local one by ligature and excision, it stands self-condemned by its complete inefficiency. It may be summed up as a vain attempt to stem the collapse invariably attending snakebite by the administration of stimulants, such as alcohol, ether, ammonia, &c. The attempt is vain, for a person in collapse from snakebite cannot be stimulated by any of these remedies, since neither the heart nor the nerve centres respond to them in the slightest degree, as they do in the absence of snake-poison, the only one that has any effect at all in slight cases being ammonia. But the attempt is not only in vain, it is highly injurious, especially if made with the usual large doses of alcohol, for, in addition to the latter not having the slightest influence on the snake-poison and its baneful effects, they act as an anæsthetic and thus add to the existing depression, besides increasing the tendency to internal hæmorrhage.