This note is devoted to a simple proof of the generalized Leibniz rule in bounded domains. The operators under consideration are the so-called spectral Laplacian and the restricted Laplacian. Equations involving such operators have been lately considered by Constantin and Ignatova in the framework of the SQG equation \cite{ CI} in bounded domains and by two of the authors \cite{ HungJuan} in the framework of the porous medium with nonlocal pressure in bounded domains. We will use the estimates in this work in a forthcoming paper on the study of Porous Medium Equations with pressure given by Riesz-type potentials .
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