Next, How would the concoction be made in the stomach, unlesse the heart sent heat by the arteries, and therewithall some of the most fluid parts of the bloud, which help to dissolve the meat receiv'd therein? and is not the act which converts the juice of these meats into bloud easie to be known, if we consider, that it is distill'd by passing and repassing the heart, perhaps more then one or two hundred times a day? And what need we ought else to explain the nutrition and the production of divers humours which are in the body, but to say, that the force wherewith the bloud in rarifying it self, passeth from the heart towards the extremities or the arteries, causeth some of its parts to stay amongst those of the members where they are, and there take the place of some others, which they drive from thence? And that according to the situation, or the figure, or the smalnesse of the pores which they meet, some arrive sooner in one place then others. In the same manner as we may have seen in severall sieves, which being diversly pierc'd, serve to sever divers grains one from the other. And briefly, that which is most remarkable herein, is the generation of the animal spirits, which are as a most subtil wind, or rather, as a most pure and lively flame, which continually rising in great abundance from the heart to the brain, dischargeth it self thence by the nerves into the muscles, and gives motion to all the members; without imagining any other reason which might cause these parts of the bloud, which being most mov'd, and the most penetrating, are the most fit to form these spirits, tend rather towards the brain, then to any other part. Save onely that the arteries which carry them thither, are those which come from the heart in the most direct line of all: And that according to the rules of the Mechanicks, which are the same with those of Nature, when divers things together strive to move one way, where there is not room enough for all; so those parts of bloud which issue from the left concavity of the heart tend towards the brain, the weaker and less agitated are expell'd by the stronger, who by that means arrive there alone.