The 2019 Henderson Tennis Open was a professional tennis tournament played on outdoor hard courts. It was the eleventh edition of the tournament which was part of the 2019 ITF Women's World Tennis Tour. It took place in Las Vegas, United States between 4 and 10 November 2019.
Singles main-draw entrants
Seeds
1 Rankings are as of 21 October 2019.
Other entrants
The following players received wildcards into the singles main draw: Jamie Loeb Grace Min Katerina Stewart Fanny Stollár
The following player received a special exempt into the singles main draw: Alexa Glatch
The following players received entry from the qualifying draw: Vladica Babić Charlotte Chavatipon Quinn Gleason María Gutiérrez Carrasco Alycia Parks Natasha Subhash Stephanie Wagner Marcela Zacarías
The following player received entry as a lucky loser: Giuliana Olmos
Champions
Singles
Mayo Hibi def. Anhelina Kalinina, 6–2, 5–7, 6–2
Doubles
Olga Govortsova / Mandy Minella def. Sophie Chang / Alexandra Mueller, 6–3, 6–4