Clarkton Depot is a historic train station located at Clarkton, Bladen County, North Carolina. It was built as a passenger and freight station by the Seaboard Air Line Railroad in 1915. It is a one-story, rectangular frame building measuring 30 feet by 90 feet. The station served the SAL's daily passenger train from Wilmington to its Charlotte station in Charlotte via Hamlet and Monroe.
It was moved to the present site in October 1975. It was added to the National Register of Historic Places in 1987.