Downing station, also known as the Depot Museum, is a historic train station located at Downing, Schuyler County, Missouri. It was built in 1872 by the Keokuk & Western Railroad. It is a one-story, frame building with board and batten siding. The building features a gable roof with wide overhanging eaves and ornate cross stickwork brackets. It was moved to its present location in 1976, and houses a local history museum.
It was added to the National Register of Historic Places in 1983 as the Downing Railroad Depot.