The 1980 United States Senate election in Maryland took place on November 4, 1980.
Incumbent Republican U.S Senator Charles Mathias won re-election to a third term in a landslide, defeating Democratic State Senator Edward T. Conroy.
As of , this is the last time a Republican won a U.S. Senate election in Maryland. It is also the last time a Republican won Prince George's County and Baltimore City in a statewide election.
Republican primary
Candidates
Roscoe Bartlett
John M. Brennan
Jack Fortune Holden
Charles Mathias, incumbent Senator
V. Dallas Merrell
Gerald G. Warren
Results
Democratic primary
Candidates
Frank J. Broschart, candidate for U.S. Representative in 1972
Edward T. Conroy, State Senator from Bowie
Mello Cottone
Victor Crawford, State Senator from Silver Spring
Robert L. Douglass, State Senator from Baltimore
John A. Kennedy
Dennis C. McCoy, Delegate from Baltimore
R. Spencer Oliver, Chief of Staff of the Commission on Security and Cooperation in Europe David E. Shaw Kurt Summers Richard J. Taranto James A. Young
Results
General election
Results
Results by county
Counties that flipped from Democrat to Republican
Baltimore (County) Baltimore (City)