George Armistead Smathers (November 14, 1913 – January 20, 2007) was an American lawyer and politician. He was a member of the United States Senate from 1951 until 1969 from Florida. He was also a member of the United States House of Representatives from 1947 to 1951. He was a member of the Democratic Party.
In 1960, Smathers ran as a “Favorite Son” for President of the United States. He won the Florida Democratic primary, becoming the first Floridian popularly elected to represent Florida as a presidential candidate at a national convention. In 1968, Floridians again nominated Smathers as their Favorite Son candidate for president.
Smathers died on January 20, 2007 in Indian Creek, Florida from a stroke, aged 93.