Argüello () is a Spanish surname, most commonly associated with the early settlers in the cities of Granada, Nicaragua and of Córdoba, Argentina, as well as throughout Mexico and, in the United States, in what is now the state of California, the so-called Californio Argüellos.

A list of politicians and other notables bearing the surname in the above countries, as well as in a few others, ordered by date of birth, follows:

Argüello

Eminent Argentineans

Jorge Argüello (born 1956), politician and diplomat

Roberto Argüello (born 1963), former tennis player

Facundo Argüello (footballer) (born 1979), footballer

Martín Vassallo Argüello (born 1980), former tennis player

Marcos Argüello (born 1981), goalkeeper

Facundo Argüello (tennis) (born 1992), tennis player

Irma Arguello, (b. 1970) international security expert

Noteworthy Nicaraguans

Argüello