Scarborough is a surname of English origin. Notable people with the surname include:
Adrian Scarborough (born 1968), English actor
Andrew Scarborough (born 1973), English actor
Chuck Scarborough (born 1943), American television news anchor
David Scarboro (1968–1988), English actor (EastEnders) Edmund Scarborough (c.1617–1671), Virginia politician, soldier and landowner Edmund Scarborough (1840-?), Mississippi politician, minister and farmer Elizabeth Ann Scarborough (born 1947), American fantasy/science fiction writer George Scarborough (1859–1900), an American Western lawman and outlaw J. Gifford Scarborough (died 1969), American politician and lawyer Joe Scarborough (born 1938), English painter of humorous scenes of the life and people in South Yorkshire Joe Scarborough (born 1963), American politician, cable TV news personality, and musician Kelvin Scarborough (1964–2020), American baseball player Lee Rutland Scarborough (1870–1945), American Southern Baptist pastor Robert H. Scarborough (1923–2020) United States Coast Guard vice admiral William Sanders Scarborough (1852–1926), American classics scholar Eve Scarborough (born 1999), a subject of the BBC documentary film series Child of Our Time